Senior Patient Safety Investigator

Remote, USA
Posted Jun 13, 2026
Full-time

Job Family:

Technology Consulting


Travel Required:

Up to 10%


Clearance Required:

Ability to Obtain Public Trust

What You Will Do:

The Senior Patient Safety Investigator plays a critical role in establishing and operating a national patient safety function capable of managing a high volume of incoming and in‑flight safety complaints while driving systemic learning and long‑term improvement.

This role sits at the “middle” of the patient safety lifecycle—bridging intake and triage with investigation, escalation, closure, and post‑case learning. The individual will apply deep clinical judgment, standardized safety processes, and data‑driven insight to ensure that complaints are addressed consistently, escalated appropriately, and translated into actionable policy and operational improvements.

Intake, Triage & Case Management

  • Receive and acknowledge patient safety complaints from multiple intake channels (member‑submitted, patient‑submitted, call center, web‑based)

    Conduct rapid clinical triage (often within 24 hours) to assess urgency and potential patient risk

    Apply standardized risk stratification (high / moderate / low) using defined clinical and operational criteria

    Identify duplicate or related complaints and ensure appropriate case linkage

    Serve as case owner, maintaining accountability from intake through closure

    Investigation & Escalation

    • Perform clinically grounded investigations, including:

      Review of clinical narratives and supporting documentation

      Identification of systemic versus isolated issues

      Execute defined escalation pathways, including:

      Internal leadership notification

      Formal inquiries

      Referral to MPSC or other oversight bodies as appropriate

      Clearly document findings, decisions, and rationale within the case management system

    Process & Program Development

    • Operationalize standardized patient safety workflows while recognizing the unique nature of individual cases

      Help define and refine: Triage criteria, escalation thresholds and case closure standards

      Support transition strategies for legacy cases, including close‑out approaches and intake of new complaints into modern systems

      Learning, Feedback & Policy Improvement

      • Contribute to formal post‑case feedback loops to identify trends, recurring risks, and systemic gaps

        Translate aggregated case insights into: Policy recommendations, Updated guidance and training or communication needs

        Support transparency and leadership reporting to strengthen public trust in the OPTN patient safety function

        Technology & Data Enablement

        • Actively use and help shape a case management platform

          Ensure accurate, timely documentation to support: Workflow tracking, dashboards and leadership reporting and prevention of cases falling through the cracks

          Partner with technology teams to ensure clinical workflows are reflected accurately in system design

          Maintain strict compliance with HIPAA, PHI/PII handling, and federal security requirements


          What You Will Need:

          Registered Nurse (RN) required; advanced clinical leadership experience strongly preferred

          10+ years of progressive clinical experience in acute care, perioperative, critical care, transplant, or related high‑acuity environments

          Demonstrated experience exercising independent clinical judgment in complex, high‑risk situations

          Proven experience in: Patient safety investigations, quality improvement and risk management or compliance.

          Ability to assess clinical risk rapidly and consistently across diverse scenarios

          Experience balancing standardized processes with case‑specific nuance

          Experience working with EHRs and/or case management systems

          Ability to adopt and help operationalize new technology platforms

          Comfort using dashboards, reports, and structured data to support leadership decision‑making.

          What Would Be Nice To Have:

          Experience with organ donation, transplant services, or OPO operations

          Prior work in federally regulated or oversight environments

          Experience standing up new programs, workflows, or operating models

          Experience leading or managing multidisciplinary clinical teams

          Strong documentation, decision‑making, and escalation skills

          Comfort operating in environments with high case volume and competing priorities

          Ability to function effectively with limited external resourcing and tight timelines

          MBA, MHA, or similar advanced degree

          Prior involvement in large‑scale clinical operations (>200 FTEs or multi‑site systems)

          The annual salary range for this position is $102,000.00-$170,000.00. Compensation decisions depend on a wide range of factors, including but not limited to skill sets, experience and training, security clearances, licensure and certifications, and other business and organizational needs.


          What We Offer:

          Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.

          Benefits include:

          Medical, Rx, Dental & Vision Insurance

          Personal and Family Sick Time & Company Paid Holidays

          Position may be eligible for a discretionary variable incentive bonus

          Parental Leave and Adoption Assistance

          401(k) Retirement Plan

          Basic Life & Supplemental Life

          Health Savings Account, Dental/Vision & Dependent Care Flexible Spending Accounts

          Short-Term & Long-Term Disability

          Student Loan PayDown

          Tuition Reimbursement, Personal Development & Learning Opportunities

          Skills Development & Certifications

          Employee Referral Program

          Corporate Sponsored Events & Community Outreach

          Emergency Back-Up Childcare Program

          Mobility Stipend

          About Guidehouse

          Guidehouse is an Equal Opportunity Employer–Protected Veterans, Individuals with Disabilities or any other basis protected by law, ordinance, or regulation.

          Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance including the Fair Chance Ordinance of Los Angeles and San Francisco.

          If you have visited our website for information about employment opportunities, or to apply for a position, and you require an accommodation, please contact Guidehouse Recruiting at 1-571-633-1711 or via email at RecruitingAccommodation@guidehouse.com. All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodation.

          All communication regarding recruitment for a Guidehouse position will be sent from Guidehouse email domains including @guidehouse.com or guidehouse@myworkday.com.  Correspondence received by an applicant from any other domain should be considered unauthorized and will not be honored by Guidehouse.  Note that Guidehouse will never charge a fee or require a money transfer at any stage of the recruitment process and does not collect fees from educational institutions for participation in a recruitment event. Never provide your banking information to a third party purporting to need that information to proceed in the hiring process.

          If any person or organization demands money related to a job opportunity with Guidehouse, please report the matter to Guidehouse’s Ethics Hotline. If you want to check the validity of correspondence you have received, please contact recruiting@guidehouse.com. Guidehouse is not responsible for losses incurred (monetary or otherwise) from an applicant’s dealings with unauthorized third parties.

          Guidehouse does not accept unsolicited resumes through or from search firms or staffing agencies. All unsolicited resumes will be considered the property of Guidehouse and Guidehouse will not be obligated to pay a placement fee.

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