Senior Software Engineer, AI - UpDoc

Remote, USA
Posted Jun 14, 2026
Full-time

About UpDoc

At UpDoc, we are building the world's first clinically validated, physician-supervised conversational agent that manages chronic diseases; the first step towards a true "AI doctor". With partners including Stanford, Mayo Clinic, Eli Lilly, UCSF Health, and Microsoft, UpDoc is working to build a future where all patients can access high-quality, high-touch care. Learn more about us here.

We are seeking a talented and motivated senior engineer to join our team. You will primarily work on UpDoc’s patient-facing conversational agent. This is a fully remote position.

Who You Are

You’re an experienced senior engineer with a backend tilt. You’re well-versed in all things web and have experience building LLM applications end-to-end, even if not in a professional context. You follow the AI/LLM space closely, play with new technologies as they come out, and are excited to use these technologies to build safe, reliable medical AI systems.

What You'll Do

Lead the development of our patient-facing conversational agent

Implement a scalable, low-latency system for voice/multimodal conversations

Implement rigorous prompt engineering processes and develop useful metrics for system evaluation

Identify where fine-tuning and alignment might be valuable, and create data pipelines to enable fast experimentation

Work with other backend engineers to deploy AI models and chat/voice APIs

Help identify, evaluate, and implement emerging LLM technologies, tools and frameworks

Collaborate with clinical experts to validate performance and medical accuracy

Work on developing backend services using FastAPI and Pydantic

What You’ll Need

5+ years of professional software development experience, including 2+ years of experience with backend web development

Experienced and comfortable working with type-hinted, modern Python

2+ years of experience building end-to-end LLM applications, personally or professionally

Experience integrating/optimizing LLMs in production environments

Knowledge of evaluation frameworks

Knowledge and experience with MLOps/LLMOps best practices

Experience building AI infrastructure from 0 -> 1

Experience with cloud platforms (especially Azure) and containerization technologies

Highly Desired

Professional experience building end-to-end LLM-powered applications

Experience with model fine-tuning/alignment

Experience in an early stage startup environment

Experience with healthcare industry standards, such as FHIR, and regulations, including HIPAA and SOC 2

Why You Should Join Us

Join a small, high-impact team building the future of healthcare

Work with cutting-edge LLM tools that support world-class medical institutions

Shape core technical architecture in an emerging field

Competitive compensation and equity in an early-stage startup

Interview Process

Application form

Conversation with our CTO

Technical interviews:

Coding interview focused on a real-world application relevant to the role (e.g., LLMs, backend engineering)

Architecture/whiteboarding interview focused on discussing general application-design relevant to the role

Conversation with our CEO

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